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The Legionella Effector RavZ Inhibits Host Autophagy Through Irreversible Atg8 Deconjugation
Eukaryotic cells can use the autophagy pathway to defend against microbes that gain access to the cytosol or reside in pathogen-modified vacuoles. It remains unclear if pathogens have evolved specific mechanisms to manipulate autophagy. Here we find that the intracellular pathogen Legionella pneumop...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3682818/ https://ncbi.nlm.nih.gov/pubmed/23112293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1227026 |
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