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Zscan4 restores the developmental potency of embryonic stem cells
The developmental potency of mouse embryonic stem (ES) cells, which is the ability to contribute to a whole embryo is known to deteriorate during long-term cell culture. Previously we have shown that ES cells oscillate between Zscan4(-) and Zscan4(+) states, and the transient activation of Zscan4 is...
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| Главные авторы: | , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3682791/ https://ncbi.nlm.nih.gov/pubmed/23739662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2966 |
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