Transient bursts of Zscan4 expression are accompanied by the rapid derepression of heterochromatin in mouse embryonic stem cells

Mouse embryonic stem cells (mESCs) have a remarkable capacity to maintain normal genome stability and karyotype in culture. We previously showed that infrequent bursts of Zscan4 expression (Z4 events) are important for the maintenance of telomere length and genome stability in mESCs. However, the mo...

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Detalhes bibliográficos
Publicado no:DNA Res
Main Authors: Akiyama, Tomohiko, Xin, Li, Oda, Mayumi, Sharov, Alexei A., Amano, Misa, Piao, Yulan, Cadet, J. Scotty, Dudekula, Dawood B., Qian, Yong, Wang, Weidong, Ko, Shigeru B. H., Ko, Minoru S. H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596397/
https://ncbi.nlm.nih.gov/pubmed/26324425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/dnares/dsv013
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