Transient bursts of Zscan4 expression are accompanied by the rapid derepression of heterochromatin in mouse embryonic stem cells

Mouse embryonic stem cells (mESCs) have a remarkable capacity to maintain normal genome stability and karyotype in culture. We previously showed that infrequent bursts of Zscan4 expression (Z4 events) are important for the maintenance of telomere length and genome stability in mESCs. However, the mo...

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Dades bibliogràfiques
Publicat a:DNA Res
Autors principals: Akiyama, Tomohiko, Xin, Li, Oda, Mayumi, Sharov, Alexei A., Amano, Misa, Piao, Yulan, Cadet, J. Scotty, Dudekula, Dawood B., Qian, Yong, Wang, Weidong, Ko, Shigeru B. H., Ko, Minoru S. H.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Full Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596397/
https://ncbi.nlm.nih.gov/pubmed/26324425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/dnares/dsv013
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