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Zscan4 transiently reactivates early embryonic genes during the generation of induced pluripotent stem cells
The generation of induced pluripotent stem cells (iPSCs) by the forced expression of defined transcription factors in somatic cells holds great promise for the future of regenerative medicine. However, the initial reprogramming mechanism is still poorly understood. Here we show that Zscan4, expresse...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3250575/ https://ncbi.nlm.nih.gov/pubmed/22355722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00208 |
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