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Effects of the antianginal drug, ranolazine, on the brain sodium channel Na(V)1.2 and its modulation by extracellular protons

BACKGROUND AND PURPOSE: Ranolazine is an antianginal drug currently approved for treatment of angina pectoris in the United States. Recent studies have focused on its effects on neuronal channels and its possible therapeutic uses in the nervous system. We characterized how ranolazine affects the bra...

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Detalhes bibliográficos
Main Authors: Peters, CH, Sokolov, S, Rajamani, S, Ruben, PC
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682716/
https://ncbi.nlm.nih.gov/pubmed/23472826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12150
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