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Developmentally Regulated Linker Histone H1c Promotes Heterochromatin Condensation and Mediates Structural Integrity of Rod Photoreceptors in Mouse Retina

Mature rod photoreceptor cells contain very small nuclei with tightly condensed heterochromatin. We observed that during mouse rod maturation, the nucleosomal repeat length increases from 190 bp at postnatal day 1 to 206 bp in the adult retina. At the same time, the total level of linker histone H1...

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Autors principals: Popova, Evgenya Y., Grigoryev, Sergei A., Fan, Yuhong, Skoultchi, Arthur I., Zhang, Samuel S., Barnstable, Colin J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682587/
https://ncbi.nlm.nih.gov/pubmed/23645681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.452144
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