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Histone Deacetylase 1 Is Essential for Rod Photoreceptor Differentiation by Regulating Acetylation at Histone H3 Lysine 9 and Histone H4 Lysine 12 in the Mouse Retina

Histone acetylation has a regulatory role in gene expression and is necessary for proper tissue development. To investigate the specific roles of histone deacetylases (HDACs) in rod differentiation in neonatal mouse retinas, we used a pharmacological approach that showed that inhibition of class I b...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Ferreira, Renata C., Popova, Evgenya Y., James, Jessica, Briones, Marcelo R. S., Zhang, Samuel S., Barnstable, Colin J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313111/
https://ncbi.nlm.nih.gov/pubmed/28028172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.756643
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