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Dynamic condensation of linker histone C-terminal domain regulates chromatin structure

The basic and intrinsically disordered C-terminal domain (CTD) of the linker histone (LH) is essential for chromatin compaction. However, its conformation upon nucleosome binding and its impact on chromatin organization remain unknown. Our mesoscale chromatin model with a flexible LH CTD captures a...

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Detalhes bibliográficos
Main Authors: Luque, Antoni, Collepardo-Guevara, Rosana, Grigoryev, Sergei, Schlick, Tamar
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081093/
https://ncbi.nlm.nih.gov/pubmed/24906881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku491
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