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Dynamic condensation of linker histone C-terminal domain regulates chromatin structure

The basic and intrinsically disordered C-terminal domain (CTD) of the linker histone (LH) is essential for chromatin compaction. However, its conformation upon nucleosome binding and its impact on chromatin organization remain unknown. Our mesoscale chromatin model with a flexible LH CTD captures a...

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Bibliografske podrobnosti
Main Authors: Luque, Antoni, Collepardo-Guevara, Rosana, Grigoryev, Sergei, Schlick, Tamar
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081093/
https://ncbi.nlm.nih.gov/pubmed/24906881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku491
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