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Dynamic condensation of linker histone C-terminal domain regulates chromatin structure
The basic and intrinsically disordered C-terminal domain (CTD) of the linker histone (LH) is essential for chromatin compaction. However, its conformation upon nucleosome binding and its impact on chromatin organization remain unknown. Our mesoscale chromatin model with a flexible LH CTD captures a...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4081093/ https://ncbi.nlm.nih.gov/pubmed/24906881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku491 |
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