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Dynamic condensation of linker histone C-terminal domain regulates chromatin structure

The basic and intrinsically disordered C-terminal domain (CTD) of the linker histone (LH) is essential for chromatin compaction. However, its conformation upon nucleosome binding and its impact on chromatin organization remain unknown. Our mesoscale chromatin model with a flexible LH CTD captures a...

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Sonraí Bibleagrafaíochta
Main Authors: Luque, Antoni, Collepardo-Guevara, Rosana, Grigoryev, Sergei, Schlick, Tamar
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081093/
https://ncbi.nlm.nih.gov/pubmed/24906881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku491
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