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Reactive Intermediates in Cytochrome P450 Catalysis

Recently, we reported the spectroscopic and kinetic characterizations of cytochrome P450 compound I in CYP119A1, effectively closing the catalytic cycle of cytochrome P450-mediated hydroxylations. In this minireview, we focus on the developments that made this breakthrough possible. We examine the i...

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Autors principals: Krest, Courtney M., Onderko, Elizabeth L., Yosca, Timothy H., Calixto, Julio C., Karp, Richard F., Livada, Jovan, Rittle, Jonathan, Green, Michael T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682513/
https://ncbi.nlm.nih.gov/pubmed/23632017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R113.473108
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