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Solid-Phase Synthesis of C-Terminal Peptide Libraries for Studying the Specificity of Enzymatic Protein Prenylation
Prenylation is an essential post-translational modification in all eukaryotes. Here we describe the synthesis of a 340-member library of peptides containing free C-termini on cellulose membranes. The resulting library was then used to probe the specificity of protein farnesyltransferase from S. cere...
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Hoofdauteurs: | , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2012
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3682486/ https://ncbi.nlm.nih.gov/pubmed/22783549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc31713c |
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