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The NusA N-terminal domain is necessary and sufficient for enhancement of transcriptional pausing via interaction with the RNA exit channel of RNA polymerase
NusA is a core regulator of transcript elongation that is well conserved in bacteria and archaea. NusA interacts with elongating complexes and the nascent RNA transcript in ways that stimulate pausing and termination but can be switched to anti-pausing and anti-termination by other accessory protein...
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Huvudupphovsmän: | , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
2010
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3682478/ https://ncbi.nlm.nih.gov/pubmed/20600118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.06.036 |
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