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The NusA N-terminal domain is necessary and sufficient for enhancement of transcriptional pausing via interaction with the RNA exit channel of RNA polymerase

NusA is a core regulator of transcript elongation that is well conserved in bacteria and archaea. NusA interacts with elongating complexes and the nascent RNA transcript in ways that stimulate pausing and termination but can be switched to anti-pausing and anti-termination by other accessory protein...

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Bibliographic Details
Main Authors: Ha, Kook Sun, Toulokhonov, Innokenti, Vassylyev, Dmitry G., Landick, Robert
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682478/
https://ncbi.nlm.nih.gov/pubmed/20600118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.06.036
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