Therapeutic efficacy of CXCR3 blockade in an experimental model of severe sepsis

INTRODUCTION: In our previous studies we demonstrated that CXC chemokine receptor 3 (CXCR3) participates in the regulation of lymphocyte trafficking during cecal ligation and puncture (CLP)-induced sepsis. In this study, we evaluated the effects of treatment with anti-CXCR3 immunoglobulin (IgG) and...

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Detalhes bibliográficos
Main Authors: Herzig, Daniela S, Guo, Yin, Fang, Geping, Toliver-Kinsky, Tracy E, Sherwood, Edward R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682267/
https://ncbi.nlm.nih.gov/pubmed/22992408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc11642
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