The role of interferon-γ in the pathogenesis of acute intra-abdominal sepsis

Several studies indicate that IFN-γ facilitates systemic inflammation during endotoxin-induced shock. However, the pathobiology of IFN-γ in clinically relevant models of septic shock, such as CLP, is not well understood. In this study, the role of IFN-γ in the pathogenesis of CLP-induced septic shoc...

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Detalhes bibliográficos
Main Authors: Romero, Christopher R., Herzig, Daniela S., Etogo, Anthony, Nunez, Jesus, Mahmoudizad, Rod, Fang, Geping, Murphey, E. D., Toliver-Kinsky, Tracy, Sherwood, Edward R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2010
Assuntos:
Inflammation, Extracellular Mediators, & Effector Molecules
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974432/
https://ncbi.nlm.nih.gov/pubmed/20628064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0509307
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