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STAT1-deficient Mice are Resistant to CLP-induced Septic Shock

STAT1 is a member of the JAK-STAT signaling family and plays a key role in facilitating gene transcription in response to activation of the Type I and Type II interferon (IFN) receptors. TYK2 is essential for type I, but not type II, IFN-induced STAT1 activation. Previous studies show that STAT1-def...

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Détails bibliographiques
Auteurs principaux: Herzig, Daniela, Fang, Geping, Toliver-Kinsky, Tracy E., Guo, Yin, Bohannon, Julia, Sherwood, Edward R.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445722/
https://ncbi.nlm.nih.gov/pubmed/22777121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e318265a2ab
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