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STAT1-deficient Mice are Resistant to CLP-induced Septic Shock
STAT1 is a member of the JAK-STAT signaling family and plays a key role in facilitating gene transcription in response to activation of the Type I and Type II interferon (IFN) receptors. TYK2 is essential for type I, but not type II, IFN-induced STAT1 activation. Previous studies show that STAT1-def...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3445722/ https://ncbi.nlm.nih.gov/pubmed/22777121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e318265a2ab |
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