Lataa...
Functional effects of 13 rare PRSS1 variants presumed to cause chronic pancreatitis
OBJECTIVE: Hereditary pancreatitis is caused by mutations in human cationic trypsinogen (PRSS1) which lead to increased autoactivation by altering chymotrypsin C (CTRC)-dependent trypsinogen activation and degradation. Exceptions are some cysteine mutations which cause misfolding, intracellular rete...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3681892/ https://ncbi.nlm.nih.gov/pubmed/23455445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2012-304331 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|