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Human cationic trypsinogen (PRSS1) variants and chronic pancreatitis

Variations in the serine protease 1 (PRSS1) gene encoding human cationic trypsinogen have been conclusively associated with autosomal dominant hereditary pancreatitis and sporadic nonalcoholic chronic pancreatitis. Most high-penetrance PRSS1 variants increase intrapancreatic trypsin activity by stim...

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Autors principals: Németh, Balázs Csaba, Sahin-Tóth, Miklós
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949028/
https://ncbi.nlm.nih.gov/pubmed/24458023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00419.2013
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