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Human cationic trypsinogen (PRSS1) variants and chronic pancreatitis
Variations in the serine protease 1 (PRSS1) gene encoding human cationic trypsinogen have been conclusively associated with autosomal dominant hereditary pancreatitis and sporadic nonalcoholic chronic pancreatitis. Most high-penetrance PRSS1 variants increase intrapancreatic trypsin activity by stim...
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Autors principals: | , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
American Physiological Society
2014
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949028/ https://ncbi.nlm.nih.gov/pubmed/24458023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00419.2013 |
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