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Prospect of Bioflavonoid Fisetin as a Quadruplex DNA Ligand: A Biophysical Approach

Quadruplex (G(4)) forming sequences in telomeric DNA and c-myc promoter regions of human DNA are associated with tumorogenesis. Ligands that can facilitate or stabilize the formation and increase the stabilization of G(4) can prevent tumor cell proliferation and have been regarded as potential anti-...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sengupta, Bidisha, Pahari, Biswapathik, Blackmon, Laura, Sengupta, Pradeep K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681855/
https://ncbi.nlm.nih.gov/pubmed/23785423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065383
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