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Prospect of Bioflavonoid Fisetin as a Quadruplex DNA Ligand: A Biophysical Approach

Quadruplex (G(4)) forming sequences in telomeric DNA and c-myc promoter regions of human DNA are associated with tumorogenesis. Ligands that can facilitate or stabilize the formation and increase the stabilization of G(4) can prevent tumor cell proliferation and have been regarded as potential anti-...

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Détails bibliographiques
Auteurs principaux: Sengupta, Bidisha, Pahari, Biswapathik, Blackmon, Laura, Sengupta, Pradeep K.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681855/
https://ncbi.nlm.nih.gov/pubmed/23785423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065383
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