Phosphorylation of centromeric histone H3 variant regulates chromosome segregation in Saccharomyces cerevisiae

The centromeric histone H3 variant (CenH3) is essential for chromosome segregation in eukaryotes. We identify posttranslational modifications of Saccharomyces cerevisiae CenH3, Cse4. Functional characterization of cse4 phosphorylation mutants shows growth and chromosome segregation defects when comb...

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Main Authors: Boeckmann, Lars, Takahashi, Yoshimitsu, Au, Wei-Chun, Mishra, Prashant K., Choy, John S., Dawson, Anthony R., Szeto, May Y., Waybright, Timothy J., Heger, Christopher, McAndrew, Christopher, Goldsmith, Paul K., Veenstra, Timothy D., Baker, Richard E., Basrai, Munira A.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2013
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681705/
https://ncbi.nlm.nih.gov/pubmed/23637466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-12-0893
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