Phosphorylation of centromeric histone H3 variant regulates chromosome segregation in Saccharomyces cerevisiae

The centromeric histone H3 variant (CenH3) is essential for chromosome segregation in eukaryotes. We identify posttranslational modifications of Saccharomyces cerevisiae CenH3, Cse4. Functional characterization of cse4 phosphorylation mutants shows growth and chromosome segregation defects when comb...

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Autores principales: Boeckmann, Lars, Takahashi, Yoshimitsu, Au, Wei-Chun, Mishra, Prashant K., Choy, John S., Dawson, Anthony R., Szeto, May Y., Waybright, Timothy J., Heger, Christopher, McAndrew, Christopher, Goldsmith, Paul K., Veenstra, Timothy D., Baker, Richard E., Basrai, Munira A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2013
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681705/
https://ncbi.nlm.nih.gov/pubmed/23637466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-12-0893
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