Misregulation of Scm3p/HJURP Causes Chromosome Instability in Saccharomyces cerevisiae and Human Cells

The kinetochore (centromeric DNA and associated proteins) is a key determinant for high fidelity chromosome transmission. Evolutionarily conserved Scm3p is an essential component of centromeric chromatin and is required for assembly and function of kinetochores in humans, fission yeast, and budding...

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Bibliografiske detaljer
Main Authors: Mishra, Prashant K., Au, Wei-Chun, Choy, John S., Kuich, P. Henning, Baker, Richard E., Foltz, Daniel R., Basrai, Munira A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183075/
https://ncbi.nlm.nih.gov/pubmed/21980305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002303
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