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Structural Integrity of Centromeric Chromatin and Faithful Chromosome Segregation Requires Pat1

The kinetochore (centromeric DNA and associated protein complex) is essential for faithful chromosome segregation and maintenance of genome stability. Here we report that an evolutionarily conserved protein Pat1 is a structural component of Saccharomyces cerevisiae kinetochore and associates with ce...

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Autors principals: Mishra, Prashant K., Ottmann, Alicia R., Basrai, Munira A.
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781966/
https://ncbi.nlm.nih.gov/pubmed/23893485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.155291
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