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IgA response in preterm neonates shows little evidence of antigen-driven selection

After birth, contact to environmental antigens induces the production of IgA, which represents a first line of defense for the neonate. We sought to characterize the maturation of the repertoire of IgA H chain transcripts in circulating blood B cells during human ontogeny. We found that IgA H chain...

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Bibliographische Detailangaben
Hauptverfasser: Rogosch, Tobias, Kerzel, Sebastian, Hoß, Katharina, Hoersch, Gabriele, Zemlin, Cosima, Heckmann, Matthias, Berek, Claudia, Schroeder, Harry W., Maier, Rolf F., Zemlin, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681535/
https://ncbi.nlm.nih.gov/pubmed/23105134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103347
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