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RNA polymerase II transcription factors H4TF-1 and H4TF-2 require metal to bind specific DNA sequences.
Specific DNA-binding and in vitro transcription activities of H4TF-1 and H4TF-2 are inactivated by chelating agents. Binding activity is restored by addition of Zn2+, and H4TF-2 is also reactivated by Fe2+. In contrast, preformed factor-DNA complexes are resistant to chelators. Therefore, metal ions...
Tallennettuna:
| Julkaisussa: | Mol Cell Biol |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Taylor & Francis
1987
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368148/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3437898/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.12.4582 |
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