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HIF1A employs CDK8-Mediator to stimulate RNAPII elongation
The transcription factor HIF1A is a key mediator of the cellular response to hypoxia. Despite the importance of HIF1A in homeostasis and various pathologies, little is known about how it regulates RNA polymerase II (RNAPII). We report here that HIF1A employs a specific variant of the Mediator comple...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3681429/ https://ncbi.nlm.nih.gov/pubmed/23746844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.04.048 |
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