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CDK8 is a positive regulator of transcriptional elongation within the serum response network

The Mediator complex allows communication between transcription factors and RNA polymerase II (RNAPII). CDK8, the kinase found in some variants of Mediator, has been characterized mostly as a transcriptional repressor. Recently, CDK8 was demonstrated to be a potent oncoprotein. Here we show that CDK...

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Detalhes bibliográficos
Main Authors: Donner, Aaron J., Ebmeier, Christopher C., Taatjes, Dylan J., Espinosa, Joaquín M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920286/
https://ncbi.nlm.nih.gov/pubmed/20098423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1752
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