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CDK8 is a positive regulator of transcriptional elongation within the serum response network
The Mediator complex allows communication between transcription factors and RNA polymerase II (RNAPII). CDK8, the kinase found in some variants of Mediator, has been characterized mostly as a transcriptional repressor. Recently, CDK8 was demonstrated to be a potent oncoprotein. Here we show that CDK...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2920286/ https://ncbi.nlm.nih.gov/pubmed/20098423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1752 |
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