COX2-derived primary and cyclopentenone prostaglandins are increased after asphyxial cardiac arrest

BACKGROUND: Cyclopentenone prostaglandins have been identified as potential neurotoxic agents in the setting of hypoxia-ischemia. Cyclooxygenase-2 (COX-2), the upstream enzyme responsible for prostaglandin production is upregulated following hypoxic-ischemic brain injury. However, the temporal produ...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Hao, Rose, Marie E., Miller, Tricia M., Li, Wenjin, Shinde, Sunita N., Pickrell, Alicia M., Poloyac, Samuel M., Graham, Steven H., Hickey, Robert W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681205/
https://ncbi.nlm.nih.gov/pubmed/23624225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2013.04.029
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