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Quantitative Immunohistochemistry of Desmosomal Proteins (Plakoglobin, Desmoplakin and Plakophilin), Connexin-43, and N-cadherin in Arrhythmogenic Cardiomyopathy: An Autopsy Study

BACKGROUND: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetic disorder related to mutations in desmosomal proteins. The current study tests the hypothesis that immunohistochemical staining for desmosomal proteins is of diagnostic utility by studying autopsy-confirmed cases of ARVC....

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Detalhes bibliográficos
Main Authors: Tavora, Fabio, Zhang, Mingchang, Cresswell, Nathaniel, Li, Ling, Fowler, David, Franco, Marcello, Burke, Allen
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Open 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680985/
https://ncbi.nlm.nih.gov/pubmed/23802019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874192401307010028
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