Adult diffuse gliomas produce mRNA transcripts encoding EGFR isoforms lacking a tyrosine kinase domain

The epidermal growth factor receptor (EGFR) gene encodes four alternatively spliced mRNA, variants 1, 2, 3 and 4, respectively, encoding the whole isoform a (EGFR) and truncated isoforms b, c and d, all of which lack the receptor’s intracellular domain. In addition, a mutant EGFRvIII differs from is...

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Bibliografiske detaljer
Main Authors: GUILLAUDEAU, ANGÉLIQUE, DURAND, KARINE, RABINOVITCH-CHABLE, HÉLÈNE, POMMEPUY, ISABELLE, MESTUROUX, LAURA, ROBERT, SANDRINE, CHAUNAVEL, ALAIN, MOREAU, JEAN-JACQUES, LABROUSSE, FRANÇOIS
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2011
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680776/
https://ncbi.nlm.nih.gov/pubmed/22159595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2011.1287
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