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Modulation of ventricular transient outward K(+) current by acidosis and its effects on excitation-contraction coupling

The contribution of transient outward current (I(to)) to changes in ventricular action potential (AP) repolarization induced by acidosis is unresolved, as is the indirect effect of these changes on calcium handling. To address this issue we measured intracellular pH (pH(i)), I(to), L-type calcium cu...

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Detalhes bibliográficos
Main Authors: Saegusa, Noriko, Garg, Vivek, Spitzer, Kenneth W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680771/
https://ncbi.nlm.nih.gov/pubmed/23585132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00070.2013
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