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Regulation of cardiac excitation–contraction coupling by action potential repolarization: role of the transient outward potassium current (I(to))

The cardiac action potential (AP) is critical for initiating and coordinating myocyte contraction. In particular, the early repolarization period of the AP (phase 1) strongly influences the time course and magnitude of the whole-cell intracellular Ca(2+) transient by modulating trans-sarcolemmal Ca(...

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Detalhes bibliográficos
Main Authors: Sah, Rajan, Ramirez, Rafael J, Oudit, Gavin Y, Gidrewicz, Dominica, Trivieri, Maria G, Zobel, Carsten, Backx, Peter H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342473/
https://ncbi.nlm.nih.gov/pubmed/12509475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.026468
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