Regulation of cardiac excitation–contraction coupling by action potential repolarization: role of the transient outward potassium current (I(to))

The cardiac action potential (AP) is critical for initiating and coordinating myocyte contraction. In particular, the early repolarization period of the AP (phase 1) strongly influences the time course and magnitude of the whole-cell intracellular Ca(2+) transient by modulating trans-sarcolemmal Ca(...

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Bibliografiske detaljer
Main Authors: Sah, Rajan, Ramirez, Rafael J, Oudit, Gavin Y, Gidrewicz, Dominica, Trivieri, Maria G, Zobel, Carsten, Backx, Peter H
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2003
Fag:
Topical Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342473/
https://ncbi.nlm.nih.gov/pubmed/12509475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.026468
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