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Kir6.2 is not the mitochondrial K(ATP) channel but is required for cardioprotection by ischemic preconditioning

ATP-sensitive K(+) (K(ATP)) channels that contain K(+) inward rectifier subunits of the 6.2 isotype (Kir6.2) are important regulators of the cardiac response to ischemia-reperfusion (I/R) injury. Opening of these channels is implicated in the cardioprotective mechanism of ischemic preconditioning (I...

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Auteurs principaux: Wojtovich, Andrew P., Urciuoli, William R., Chatterjee, Shampa, Fisher, Aron B., Nehrke, Keith, Brookes, Paul S.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680722/
https://ncbi.nlm.nih.gov/pubmed/23585131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00972.2012
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