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Mitochondrial ATP-sensitive potassium channel activity and hypoxic preconditioning are independent of an inwardly rectifying potassium channel subunit in C. elegans

Hypoxic preconditioning (HP) is an evolutionarily-conserved mechanism that protects an organism against stress. The mitochondrial ATP-sensitive K(+) channel (mK(ATP)) plays an essential role in the protective signaling, but remains molecularly undefined. Several lines of evidence suggest that mK(ATP...

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Autori principali: Wojtovich, Andrew P., DiStefano, Peter, Sherman, Teresa, Brookes, Paul S., Nehrke, Keith
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288502/
https://ncbi.nlm.nih.gov/pubmed/22281198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.01.021
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