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The endogenous mitochondrial complex II inhibitor malonate regulates mitochondrial ATP sensitive potassium channels: implications for ischemic preconditioning

Ischemic preconditioning (IPC) affords cardioprotection against ischemia-reperfusion (IR) injury, and while the molecular mechanisms of IPC are debated, the mitochondrial ATP sensitive K(+) channel (mK(ATP)) has emerged as a candidate effector for several IPC signaling pathways. The molecular identi...

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Detalhes bibliográficos
Main Authors: Wojtovich, Andrew P., Brookes, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2507763/
https://ncbi.nlm.nih.gov/pubmed/18433712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2008.03.025
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