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Augmented BMPRIA-Mediated BMP Signaling in Cranial Neural Crest Lineage Leads to Cleft Palate Formation and Delayed Tooth Differentiation

The importance of BMP receptor Ia (BMPRIa) mediated signaling in the development of craniofacial organs, including the tooth and palate, has been well illuminated in several mouse models of loss of function, and by its mutations associated with juvenile polyposis syndrome and facial defects in human...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Lu, Wang, Ying, Lin, Minkui, Yuan, Guohua, Yang, Guobin, Zheng, Yuqian, Chen, YiPing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680418/
https://ncbi.nlm.nih.gov/pubmed/23776616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066107
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