Mice with Tak1 Deficiency in Neural Crest Lineage Exhibit Cleft Palate Associated with Abnormal Tongue Development

Cleft palate represents one of the most common congenital birth defects in humans. TGFβ signaling, which is mediated by Smad-dependent and Smad-independent pathways, plays a crucial role in regulating craniofacial development and patterning, particularly in palate development. However, it remains la...

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Detalhes bibliográficos
Main Authors: Song, Zhongchen, Liu, Chao, Iwata, Junichi, Gu, Shuping, Suzuki, Akiko, Sun, Cheng, He, Wei, Shu, Rong, Li, Lu, Chai, Yang, Chen, YiPing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624426/
https://ncbi.nlm.nih.gov/pubmed/23460641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.432286
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