Mice with Tak1 Deficiency in Neural Crest Lineage Exhibit Cleft Palate Associated with Abnormal Tongue Development

Cleft palate represents one of the most common congenital birth defects in humans. TGFβ signaling, which is mediated by Smad-dependent and Smad-independent pathways, plays a crucial role in regulating craniofacial development and patterning, particularly in palate development. However, it remains la...

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Autori principali: Song, Zhongchen, Liu, Chao, Iwata, Junichi, Gu, Shuping, Suzuki, Akiko, Sun, Cheng, He, Wei, Shu, Rong, Li, Lu, Chai, Yang, Chen, YiPing
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624426/
https://ncbi.nlm.nih.gov/pubmed/23460641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.432286
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