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Augmented BMPRIA-Mediated BMP Signaling in Cranial Neural Crest Lineage Leads to Cleft Palate Formation and Delayed Tooth Differentiation

The importance of BMP receptor Ia (BMPRIa) mediated signaling in the development of craniofacial organs, including the tooth and palate, has been well illuminated in several mouse models of loss of function, and by its mutations associated with juvenile polyposis syndrome and facial defects in human...

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Détails bibliographiques
Auteurs principaux: Li, Lu, Wang, Ying, Lin, Minkui, Yuan, Guohua, Yang, Guobin, Zheng, Yuqian, Chen, YiPing
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680418/
https://ncbi.nlm.nih.gov/pubmed/23776616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066107
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