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Advanced Glycation End Products Induce Human Corneal Epithelial Cells Apoptosis through Generation of Reactive Oxygen Species and Activation of JNK and p38 MAPK Pathways

Advanced Glycation End Products (AGEs) has been implicated in the progression of diabetic keratopathy. However, details regarding their function are not well understood. In the present study, we investigated the effects of intracellular reactive oxygen species (ROS) and JNK, p38 MAPK on AGE-modified...

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Autors principals: Shi, Long, Yu, Xiaoming, Yang, Hongling, Wu, Xinyi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680386/
https://ncbi.nlm.nih.gov/pubmed/23776698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066781
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