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Negative Feedback Enhances Robustness in the Yeast Polarity Establishment Circuit
Many cells undergo symmetry-breaking polarization toward a randomly oriented “front” in the absence of spatial cues. In budding yeast, such polarization involves a positive feedback loop that enables amplification of stochastically arising clusters of polarity factors. Previous mathematical modeling...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3680131/ https://ncbi.nlm.nih.gov/pubmed/22500799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.03.012 |
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