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Inhibitory GEF phosphorylation provides negative feedback in the yeast polarity circuit

Cell polarity is critical for the form and function of many cell types. During polarity establishment, cells define a cortical “front” that behaves differently from the rest of the cortex. The front accumulates high levels of the active form of a polarity-determining Rho-family GTPase (Cdc42, Rac, o...

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Autori principali: Kuo, Chun-Chen, Savage, Natasha S., Chen, Hsin, Wu, Chi-Fang, Zyla, Trevin R., Lew, Daniel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018745/
https://ncbi.nlm.nih.gov/pubmed/24631237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.02.024
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