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The neonatal CNS is not conducive for encephalitogenic Th1 T cells and B cells during experimental autoimmune encephalomyelitis

Multiple sclerosis (MS) is thought to be a CD4(+) T cell mediated autoimmune demyelinating disease of the central nervous system (CNS) that is rarely diagnosed during infancy. Cellular and molecular mechanisms that confer disease resistance in this age group are unknown. We tested the hypothesis tha...

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Autori principali: Cravens, Petra D, Kieseier, Bernd C, Hussain, Rehana, Herndon, Emily, Arellano, Benjamine, Ben, Li-Hong, Timmons, Brenda C, Castro-Rojas, Cyd, Hartung, Hans-Peter, Hemmer, Bernhard, Weber, Martin S, Zamvil, Scott S, Stüve, Olaf
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679999/
https://ncbi.nlm.nih.gov/pubmed/23705890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-67
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