The neonatal CNS is not conducive for encephalitogenic Th1 T cells and B cells during experimental autoimmune encephalomyelitis

Multiple sclerosis (MS) is thought to be a CD4(+) T cell mediated autoimmune demyelinating disease of the central nervous system (CNS) that is rarely diagnosed during infancy. Cellular and molecular mechanisms that confer disease resistance in this age group are unknown. We tested the hypothesis tha...

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Detalhes bibliográficos
Main Authors: Cravens, Petra D, Kieseier, Bernd C, Hussain, Rehana, Herndon, Emily, Arellano, Benjamine, Ben, Li-Hong, Timmons, Brenda C, Castro-Rojas, Cyd, Hartung, Hans-Peter, Hemmer, Bernhard, Weber, Martin S, Zamvil, Scott S, Stüve, Olaf
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679999/
https://ncbi.nlm.nih.gov/pubmed/23705890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-67
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