A Poisson hierarchical modelling approach to detecting copy number variation in sequence coverage data

BACKGROUND: The advent of next generation sequencing technology has accelerated efforts to map and catalogue copy number variation (CNV) in genomes of important micro-organisms for public health. A typical analysis of the sequence data involves mapping reads onto a reference genome, calculating the...

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Библиографические подробности
Главные авторы: Sepúlveda, Nuno, Campino, Susana G, Assefa, Samuel A, Sutherland, Colin J, Pain5, Arnab, Clark, Taane G
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2013
Предметы:
Methodology Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679970/
https://ncbi.nlm.nih.gov/pubmed/23442253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-128
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