Development of copy number assays for detection and surveillance of piperaquine resistance associated plasmepsin 2/3 copy number variation in Plasmodium falciparum

BACKGROUND: Long regarded as an epicenter of drug-resistant malaria, Southeast Asia continues to provide new challenges to the control of Plasmodium falciparum malaria. Recently, resistance to the artemisinin combination therapy partner drug piperaquine has been observed in multiple locations across...

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Publicado en:Malar J
Autores principales: Ansbro, Megan R., Jacob, Christopher G., Amato, Roberto, Kekre, Mihir, Amaratunga, Chanaki, Sreng, Sokunthea, Suon, Seila, Miotto, Olivo, Fairhurst, Rick M., Wellems, Thomas E., Kwiatkowski, Dominic P.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Methodology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218657/
https://ncbi.nlm.nih.gov/pubmed/32404110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-020-03249-x
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