NOTCH1 mutations influence survival in chronic lymphocytic leukemia patients

BACKGROUND: NOTCH1 PEST domain mutations in chronic lymphocytic leukemia have recently been shown to be of prognostic relevance. Both NOTCH1 and NOTCH2 are constitutively activated in B-cell CLL but not expressed in normal B cells and may be involved in survival and resistance to apoptosis in CLL. W...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Willander, Kerstin, Dutta, Ravi Kumar, Ungerbäck, Jonas, Gunnarsson, Rebeqa, Juliusson, Gunnar, Fredrikson, Mats, Linderholm, Mats, Söderkvist, Peter
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2013
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679784/
https://ncbi.nlm.nih.gov/pubmed/23734977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-274
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