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Negative regulation of p53 by Ras superfamily protein RBEL1A
We had previously reported that RBEL1A, a novel Ras-like GTPase, was overexpressed in multiple human malignancies and that its depletion suppressed cell growth. However, the underlying molecular mechanism remained to be elucidated. Here we report that depletion of endogenous RBEL1A results in p53 ac...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679486/ https://ncbi.nlm.nih.gov/pubmed/23572512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.118117 |
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