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Sulindac Sulfide Differentially Induces Apoptosis in Smac-Proficient and -Deficient Human Colon Cancer Cells

Sulindac, the non-steroidal anti-inflammatory drug has shown promise in the prevention of colon cancer but the molecular mechanisms by which it mediates such effects remain to be elucidated. Sulindac sulfide is the major active metabolite of sulindac and believed to be responsible for mediating the...

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Detalhes bibliográficos
Main Authors: Shi, Jingxue, He, Qin, An, Jie, Sun, Hong, Huang, Ying, Sheikh, M. Saeed
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858416/
https://ncbi.nlm.nih.gov/pubmed/20419043
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